This morning I heard an interesting discussion between Dr Ben Goldacre (an epidemiologist) and Stephen Whitehead, chief executive of the Association of the British Pharmaceutical Industry on Radio 4 where Dr Goldacre asserts that big Pharma regularly with-hold negative clinical trial data and thereby mislead doctors and patients who subsequently take these medicines without knowing ALL of the potential risks. In addition, the regulatory bodies fail to force these companies to publish ALL of the data.
Here the discussion here (available only till 2nd October) around 2hrs 35mins into the programme. Also check out an informative (and funny) presentation by Dr Goldacre at TED below. The bit about big Pharma misleading doctors is at 7mins 40secs (but watch the whole thing)